Interstitial Granulomatous Dermatitis with Granuloma Annulare-Like Pattern Following Liposuction

We hereby report a case of a 41-year-old woman with a history of liposuction of the right hip 6 months previously who presented to her dermatologist with bilateral recurring erythematous skin nodules. On palpation, 1 cm tender nodules were identified in the bilateral hip region in close approximation to the liposuction scars and a shave biopsy was performed from the lesions on the right side. The clinical differential diagnosis included panniculitis, tumid lupus erythematosus, and infection. A biopsy was performed and the histopathologic examination revealed an interstitial palisading granulomatous dermatitis with dermal mucin deposition confirmed by colloidal iron stain (Figs. 1–3). We examined multiple H&E sections, and there was no evidence of polarizable or non-polarizable foreign material. Special stains (Gomori Methenamine silver stain [GMS], Periodic acid-Schiff [PAS], and Acid-fast bacilli stain [AFB]) were negative for fungus and mycobacteria and culture studies performed also were negative. In light of the patient’s history of liposuction immediately adjacent to the area of the nodules, we concluded that granulomatous dermatitis was induced by the liposuction procedure. There was no known history of any injectable material used in our case. The